185. "Beyond the Secretory Pathway: New Insights Into Protein Release", Chen, R.; Costa-Filho, A.; Debnath, J.; Galli, T.; Ge, L.; Goberdhan, D.; Guo, W.; He, K.; Jacob, R.; Kang, T.; Lee, M.; Li, L.; Lolicato, F.; Lu, J.; Malhotra, V.; Nickel, W.; Nikoletopoulou, V.; Ogden, S.; Sagia, G.; Shao, F.; Shi, A.; Thery, C.; Verollet, C.; Villeneuve, J.; Verweij, F.; Wang, Y.; Wang, J.; Wu, S.; Ye, Y.; Yin, H.; Yu, L.; Zhang, M.; Zhang, Y.; Zhou, X.; Zurzolo, C.; Traffic 2025, 26, e70022. [Link]

184. "Unveiling Heterogeneity: Innovations and Challenges in Single-Vesicle Analysis for Clinical Translation", Zhang, Y.; Meng, X.; Greening, David W.; Huang, Y.; Li, B.; Li, Z.; Long, G.; Lötvall, J.; Lv, L.; Poon, Ivan.; Wang, T.; Law, J.; Cai, T.; Yang, F.; Yu, L.; Zheng, L.; *Yin,H.; Journal of extracellular vesicles 2025, 14, e70209. [Link]

183. "In vivo proteomic labeling reveals diverse proteomes for therapeutic targets", Wang,Q.; Jiang,Y.; Bi, M.; Wang,G.; Xiao,Y.; Zhao, H.; Guo, Y.; Li, X.; Yue, W.; Zhang, N.; Xie, B.; Xue, Y.; Yin, H.; Zou, P.; *Li, M.; Molecular Cell 2025, S1097-2765, 00904-9. [Link]

182. "Organelle membrane-associated proteins recruit cGAS via phase separation to facilitate its membrane localization", Shi, C.; Su, C.; Zhang, K.; *Yin, H. ; eLife 2025, 1, e108566. [Link]

181. "T cell-intrinsic cGAS-CTCF regulation maintains regulatory T cell development and function", Li, H.; Zhang, Y.; Gao, S.; *Yin, H. ; Cell Rep. 2025, 44, 116302. [Link]

180. "E2-UbR74G Strategy Reveals E2-Specific Ubiquitin Conjugation Profiles in Live Cells", Shen, S.; *Yin, H. ; Nat. Chem. Biol. 2025, 21, 1089-1099. [Link]

179. "A Site-Specific Photo-Crosslinking Proteomics Approach Provides Insights into Non-Canonical Pyroptotic Caspase-4 Substrates", Zhou, Y.; Zhang, X.; *Yin, H. ; Angew. Chem. Int. Ed. 2025, 64, e202501535. [Link]

178. "EGR2 O-GlcNAcylation orchestrates protumoral macrophages development to limit CD8+ T Cell antitumor response", Zhang, Y.; Li, H.; Hao, Y.; Chen, X.; *Yin, H. ; Cell Chem. Biol. 2025, 32, 809-825. [Link]

177. "Delivering miR-23b-3p by small extracellular vesicles to promote cell senescence and aberrant lipid metabolism", Jin, Y.; Sun, G.; Chen, B.; Feng, S.; Tang, M.; Wang, H.; Zhang, Y.; Wang, Y.; An, Y.; Xiao, Y.; Liu, Z.; Liu, P.; Tian, Z.; *Yin, H.; Zhang, S.; Luan, X. ; BMC Biol. 2025, 23, 41. [Link]

176. "Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis", He, P.; Wen, C.; Zhang, X.; *Yin, H. ; J. Med. Chem. 2025, 68, 5551-5572. [Link]

175. "MyD88 self-assembles into supramolecular filaments to amplify NF-kB signaling", Wang, J.; Zhong, X.; Liao, C.; Zhang, Y.; Shen, S.; Zhang, R.; Li, G.; *Yin, H. ; Fundamental Res. 2025, In press. [Link]

174. "Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168", Ai, H.; Tong, Z.; Deng, Z.; Shi, Q.; Tao, S.; Sun, G.; Liang, J.; Sun, M.; Wu, X.; Zheng, Q.; Liang, L.; Yin, H.; Li, J.; Gao, S.; Tian, C.; Liu, L.; Pan, M. ; Nat. Chem. Biol. 2025, 21, 668-680. [Link]

173. "Targeting Toll-Like Receptor 7 as a Therapeutic Development Strategy for Systemic Lupus Erythematosus", Wang, M.; Chen, H.; Zhang, T.; Zhang, Z.; Xiang, X.; Gao, M.; Guo, Y.; Jiang, S.; Yin, K.; Chen, M.; Huang, J.; Zhong, X.; Ohto, M.; Li, J.; Shimizu, T.; *Yin, H. ; Acta Pharm. Sin. B 2024, 14, 4899-4913. [Link]

172. "Discovery of Pyrazolo[1,5-a]pyrimidine Derivatives Targeting TLR4-TLR4∗ Homodimerization via AI-Powered Next-Generation Screening", Jiang, Y. Y.; Yan, S. T.; Zhang, S. Z.; Wang, M.; Diao, W. M.; Li, J.; Fang, X. M.; *Yin, H. ; Eur. J. Med. Chem. 2024, 280, 116945. [Link]

171. "Click-Chemistry-Based Protocol for Detecting 4-Octyl- Itaconate-Alkylated Proteins in Primary Mouse Macrophages", Su, C.; Cheng, T.; Zhang, H.; *Yin, H. ; STAR Protoc. 2024, 5, 103314. [Link]

170. "Pyridine-Based Small Molecule Inhibitors of SARM1 Alleviate Cell Death Caused by NADase Activity", Tang, Q.; *Yin, H. ; Chem. Comm. 2024, 60, 8724-8727. [Link]

169. "Erythroid-Intrinsic Activation of TLR8 Impairs Erythropoiesis in Inherited Anemia", Liang, J.; Wan, Y.; Gao, J.; Wang, D.; Zheng, L.; Wu, P.; Wang, B.; Ma, Y.; An, N.; Ma, X.; Geng, G.; Tong, J.; Liu, J.; Wang, J.; Li, Y.; Shen, B.; Wang, D.; Gao, M.; Kurita, R.; Nakamura, Y.; Zhu, P.; Yin, H.; Zhu, X.; *Shi, L. ; Nat. Commun. 2024, 15, 5678. [Link]

168. "ADP-Hep-Induced Liquid Phase Condensation of TIFA-TRAF6 Activates ALPK1/TIFA-Dependent Innate Immune Responses", Li, L.; Wang, J.; Zhong, X.; Jiang, Y.; Pei, G.; Yang, X.; Zhang, K.; Shen, S.; Jin, X.; Sun, G.; Su, C.; Chen, S.; *Yin, H. ; Research 2024, 7, 0315. [Link]

167. "Editorial: Natural Product Chemical Biology", Zhang, Q.; Lei, X.; Yin, H.; Yue, J. ; Bioorg. Med. Chem. 2024, 109, 129817. [Link]