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[2022-2023][2020-2021][2018-2019][2016-2017][2014-2015][2012-2013][2008-2011][PhD&Post-Doc][Patents]

145. "SARS-CoV-2 Spike Protein Interacts with and Activates TLR4", Zhao, Y.; Kuang, M.; Li, J.; Zhu, L.; Jia, Z.; Guo, X.; Hu, Y.; Kong, J.; Yin, H.; Wang, X.; You, F. ; Cell Res 2021, 31, 818-820.. [Link]

144. "Design and Optimisation of a Small-Molecule TLR2/4 Antagonist for Anti-Tumour Therapy", Xu, Q.; Li, T.; Chen, H.; Kong, J.; Zhang, L.; *Yin, H. ; RSC Med. Chem 2021, 12, 1771-1779.. [Link]

143. "Harnessing the Therapeutic Potential of Extracellular Vesicles for Cancer Treatment", Zhang, Y.; Xiao, Y.; Sun, G.; Jin, X.; Guo, L.; Li, T.; *Yin, H. ; Semin. Cancer Biol 2021, 74, 92-104.. [Link]

142. "SARS-CoV-2 Nucleocapsid Protein Undergoes Liquid-Liquid Phase Separation into Stress Granules through Its N-Terminal Intrinsically Disordered Region", Wang, J.; Shi, C.; Xu, Q.; *Yin, H. ; Cell Discov 2021, 7, 5.. [Link]

141. "Design, Synthesis, and Structure–Activity Relationship of N-Aryl-N′-(thiophen-2-yl)thiourea Derivatives as Novel and Specific Human TLR1/2 Agonists for Potential Cancer Immunotherapy", Chen, Z.; Zhang, L.; Yang, J.; Zheng, L.; Hu, F.; Duan, S.; Nandakumar, K. S.; Liu, S.; *Yin, H.; *Cheng, K. ; J. Med. Chem 2021, 64, 7371-7389.. [Link]

140. "TLR4 Biased Small Molecule Modulators", Lin, C.; Wang, H.; Zhang, M.; Mustafa, S.; Wang, Y.; Li, H.; Yin, H.; Hutchinson, M.; Wang, X. ; Pharmacol. Ther 2021, 228, 107918.. [Link]

139. "Orthosteric-Allosteric Dual Inhibitors of PfHT1 as Selective Anti-Malarial Agents", Huang, J.; Yuan, Y.; Zhao, N.; Pu, D.; Tang, Q.; Zhang, S.; Luo, S.; Yang, X.; Wang, N.; Xiao, Y.; Zhang, T.; Liu. Z.; Sakata-Kato, Y.; Hirata, K.; *Jiang, X.; *Kato, N.; *Yan, N.; *Yin, H. ; Proc. Natl. Acad. Sci. U. S. A 2021, 118, e2017749118.. [Link]

138. "Tetrasubstituted Imidazoles as Incognito Toll-like Receptor 8 A(nta)gonists", Yang, Y.; Csakai, A.; Jiang, S.; Smith, C.; Tanji, H.; Huang, J.; Jones, T.; Sakaniwa, K; Broadwell, L.; Shi, C.; Soti, S.; Ohto, U.; Fang, Y.; Shen, S.; Deng, F.; Shimizu, T.; *Yin, H. ; Nat. Commun 2021, 12, 4351.. [Link]

137. "TLR8 and Complement C5 Induce Cytokine Release and Thrombin Activation in Human Whole Blood Challenged with Gram-Positive Bacteria", Ehrnström, B.; Kojen, J.; Giambelluca, M.; Ryan, L.; Moen, S.; Hu, Z.; Yin, H.; Mollnes, T. E.; Damås, J.; Espevik, T.; Stenvik, J. ; J. Leukoc. Biol 2020, 107, 673-683.. [Link]

136. "Discovery of Small Molecule Cyclic GMP-AMP Synthase Inhibitors", Padilla-Salinas, R.; Sun, L; Anderson, R.; Yang, X.; Zhang, S.; Chen, Z.; *Yin, H. ; J. Org. Chem 2020, 85, 1579-1600.. [Link]

135. "Switch off Parallel Circuit: Insight of New Strategy of Simultaneously Suppressing Canonical and Non-canonical Inflammation Activation in Endotoxemic Mice", Yan, L.; Liang, J.; Zhou, Y.; Huang, J.; Zhang, T.; Wang, X.; *Yin, H. ; Adv. Biosyst 2020, 4, e2000037.. [Link]

134. "Nuclear Molecular Imaging–Guided Bioorthogonal System Reveals the Antitumor Immune Function of Pyroptosis", *Yin, H. ; Acta. Phys.-Chim. Sin 2020, 36, 2004056.. [Link]

133. "The Future of Extracellular Vesicles as Theranostics", Soekmadji, C. et al. ; J. Extracell. Vesicles 2020, 9, e1809766.. [Link]

132. "Regulation of Aerobic Glycolysis to Decelerate Tumor Proliferation by Small Molecule Inhibitors Targeting Glucose Transporters", Gao, M.; Huang, J.; Jiang, X.; Yuan, Y.; Luo, S.; Wang, N.; Pang, H.; Deng, D.; Yao, C.; Lin, Z.; Pu, D.; Liu, Z.; Hu, Z.; *Yin, H. ; Protein Cell 2020, 11, 446-451.. [Link]

131. "Sensing of HIV-1 by TLR8 Activates Human T cells and Reverses Latency", Meas, H. Z.; Haug, M.; Beckwith, M. S.; Louet, C.; Ryan, L.; Hu, Z.; Landskron, J.; Nordbø, S. A.; Taskén, K.; Yin, H.; Damås, J. K.; Flo, T. H. ; Nat. Commun 2020, 11, 147.. [Link]

130. "Rationally Designed Small-Molecule Inhibitors Targeting an Unconventional Pocket on the TLR8 Protein-Protein Interface", Jiang, S.; Tanji, H.; Yin, K.; Zhang, S.; Sakaniwa, K.; Huang, J.; Yang, Y.; Li, J.; Ohto, U.; Shimizu, T.; *Yin, H. ; J. Med. Chem 2020, 63, 4117-4132.. [Link]

129. "Small Molecule Modulators of Toll-Like Receptors", Wang, Y.; Zhang, S.; Li, H.; Wang, H.; Zhang, T.; Hutchinson, M.; *Yin, H.; *Wang, X. ; Acc. Chem. Res 2020, 53, 1046-1055.. [Link]

128. "How Does an RNA Selfie Work? EV-Associated RNA in Innate Immunity as Self or Danger", Xiao, Y.; Driedonks, T.; Witwer, K.; Wang, Q.; *Yin, H. ; J. Extracell. Vesicles 2020, 9, e1793515.. [Link]

127. "Immune Profiling Before Treatment is Predictive of TLR9-Induced Antitumor Efficacy", Xu, Q.; Dai, C.; Kong, J.; Chen, H.; Feng, J.; Zhang, Y.; *Yin, H. ; Biomaterials 2020, 263, 120379.. [Link]

126. "Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum", Jiang, X.; Yuan, Y.; Huang, J.; Zhang, S.; Luo, S.; Wang, N.; Pu, D.; Zhao, N.; Tang, Q.; Hirata, K.; Yang, X.; Jiao, Y.; Sakata-Kato, Y.; Wu, J.; Yan, C.; Kato, N.; *Yin, H.; *Yan, N. ; Cell 2020, 183, 258-268.. [Link]