125. "Focusing on the Influenza Virus Polymerase Complex: Recent Progress in Drug Discovery and Assay Development", Zhang, J.; Hu, Y.; Musharrafieh, R. G.; Yin, H.; Wang, J. ; Curr. Med. Chem 2019, 26, 2243-2263.. [Link]

124. "Minimal Information for Studies of Extracellular Vesicles 2018 (MISEV2018): a Position Statement of the International Society for Extracellular Vesicles and Update of the MISEV2014 Guidelines", Thery, C. et al. ; J. Extracell. Vesicles 2019, 8, e1535750.. [Link]

123. "Photoactivatable Prodrug of Doxazolidine Targeting Exosomes", Tamura, R.; Balabanova, A.; Frakes, S. A.; Bargmann, A.; Koch, T. H.; *Yin, H. ; J. Med. Chem 2019, 62, 1959-1970.. [Link]

122. "TLR1/2 Specific Small-Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes", Cen, X.; Zhu, G.; Yang, J.; Yang, J.; Guo, J.; Jin, J.; Nandakumar, K.; Yang, W.; Yin, H.; Liu, S.; Cheng, K. ; Adv. Sci 2019, 6, e1802042.. [Link]

121. "Human TLR8 is an Important Sensor of Pyogenic Bacteria and is Attenuated by Cell Surface TLR Signaling", Moen, S. H; Ehrnström, B.; Kojen, J. F.; Beckwith, K. S.; Afset, J. E.; Damås, J. K.; Hu, Z.; Yin, H.; Espevik, T.; Stenvik, J. ; Front. Immunol 2019, 10, 1209.. [Link]

120. "Lovastatin Inhibits TLR4 Signaling in Microglia by Targeting Its Co-Receptor MD2 and Attenuates Neuropathic Pain", Peng, Y.; Zhang, X.; Zhang, T.; Grace, P. M.; Li, H.; Wang, Y.; Chen, H.; Watkins, L. R.; Hutchinson, M. R.; Yin, H.; Wang, X. ; Brain Behav. Immun 2019, 82, 432-444.. [Link]

119. "Biological Membranes in EV Biogenesis, Stability, Uptake, and Cargo Transfer: an ISEV Position Paper Arising from the ISEV Membranes and EVs Workshop", Russell, A. E. et al. ; J. Extracell. Vesicles 2019, 8, e1684862.. [Link]

118. "Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-Like Receptor 7 and 8", Padilla-Salinas, R.; Anderson, R.; Sakaniwa, K.; Zhang, S.; Nordeen, P.; Lu, C.; Shimizu, S.; *Yin, H. ; J. Med. Chem 2019, 62, 10221-10244.. [Link]

117. "Extracellular Vesicles Derived from ODN-Stimulated Macrophages Promote Their Cellular Uptake by the Transfer and Activation of Cdc42", Zhang, Y.; Jin, X.; Liang, J.; Guo, Y.; Sun, G.; Zeng, X.; *Yin, H. ; Sci. Adv 2019, 5, eaav1564.. [Link]

116. "Focusing on the Influenza Virus Polymerase Complex: Recent Progress in Drug Discovery and Assay Development", Zhang, J.; Hu, Y.; Musharrafieh, R.; Yin, H.; Wang, J.; Curr. Med. Chem. 2018. [Link]

115. "An Iterative Computational Design Approach to Increase the Thermal Endurance of a Mesophilic Enzyme", Sammond, D.; Kastelowitz, N.; Donohoe, B.; Alahuhta, M.; Lunin, V.; Sarai, N.; Yin, H.; Mittal, A.; Himmel, M.; Guss, A.; Bomble, Y.; Biotechnol Biofuels. 2018, 11:189. [Link]

114. "Small Molecule TLR8 Antagonists via Structure-Based Rational Design", Hu, Z.; Tanji, H.; Jiang, S.; Zhang, S.; Koo, K.; Chan, J.; Sakaniwa, K.; Ohto, U.; Candia, A.; Shimizu, T.; Yin, H.; Cell Chem. Biol. 2018, 25, 1286-1291. [Link]

113. "Discovery of Novel Small Molecule Inhibtors of NF-κB Signaling with Anti-Inflammatory and Anti-Cancer Properties", Zhang, L.; Shi, L.; Soars, S.; Kamps, J.; Yin, H.; J. Med. Chem. 2018, 61, 14, 5881-5899. [Link]

112. "TLR4-Dependent Fibroblast Activation Drives Persistent Organ Fibrosis in Skin and Lung", Bhattacharyya, S.; Wang, W.; Qin, W.; Cheng, K.; Coulup, S.; Chavez, S.; Jiang, S.; Raparia, K.; De Almeida, L. M.; Stehlik, C.; Tamaki, Z.; Yin, H.; Varga, J.; JCI Insight 2018, 3(13), e98850. [Link]

111. "Small Molecule Inhibition of TLR8 through Stabilization of Its Resting State", Zhang, S.; Hu, Z.; Tanji, H.; Jiang, S.; Das, N.; Li, J.; Sakaniwa, K.; Jin, J.; Bian, Y.; Ohto, U.; Shimizu, T.; Yin, H.; Nat. Chem. Biol. 2018, 14, 58-64. [Link][C&EN][CU Boulder Today]

110. "DREADDed Microglia in Pain: Implications for Spinal Inflammatory Signaling in Male Rats", Grace, P. M.; Wang, X.; Strand, K. A.; Baratta, M. V.; Zhang, Y.; Galer, E. L.; Yin, H.; Maier, S. F.; Watkins, L. R.; Exp. Neurol. 2018, 304, 125-131. [Link]

109. “Summary of the ISEV Workshop on Extracellular Vesicles as Disease Biomarkers, Held in Birmingham, UK, During December 2017”, Clayton, A.; Buschmann, D.; Byrd, J. B.; Carter, D. R. F.; Cheng, L.; Compton, C.; Daaboul G.; Devitt, A.; Falcon-Perez, J. M.; Gardiner, C.; Gustafson, D.; Harrison, P.; Helmbrecht, C.; Hendrix, A.; Hill, A.; Hoffman, A.; Jones, J. C.; Kalluri, R.; Kang, J. Y.; Kirchner, B.; Lässer, C.; Lawson, C.; Lenassi, M.; Levin, C.; Llorente, A.; Martens-Uzunova, E. S.; Möller, A.; Musante, L.; Ochiya, T.; Pink, R. C.; Tahara, H.; Wauben, M. H. M.; Webber, J. P.; Welsh, J. A.; Witwer, K. W.; Yin, H.; Nieuwland, R.; J. Extracell. Vesicles 2018, 7, e1473707. [Link]